SCHEMBL461642

SCHEMBL461642

O=S(=O)(O)c1cc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)ccc1C=Cc1ccc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)cc1S(=O)(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.61
CA1 P00915 5/20 0.61
CA2 P00918 5/20 0.61
CA9 Q16790 5/20 0.61
LMNA P02545 2/20 0.59
HTT P42858 2/20 0.59
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
MAPT P10636 4/20 0.53
POLB P06746 2/20 0.53
TP53 P04637 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
TSHR P16473 1/20 0.50
GAA P10253 1/20 0.49
PTGS2 P35354 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31121933 1.00 CA12 (0.61) CA12CA1CA2CA9LMNA
SCHEMBL461641 1.00 CA12 (0.61) CA12CA1CA2CA9LMNA
SCHEMBL30398437 1.00 CA12 (0.61) CA12CA1CA2CA9LMNA
SCHEMBL29943666 1.00 CA12 (0.61) CA12CA1CA2CA9LMNA
SCHEMBL5955270 0.99 CA12 (0.60) CA12CA1CA2CA9LMNA
SCHEMBL5382397 0.99 CA12 (0.63) CA12CA1CA2CA9LMNA
SCHEMBL5955302 0.99 CA12 (0.60) CA12CA1CA2CA9LMNA
SCHEMBL5955347 0.99 CA12 (0.63) CA12CA1CA2CA9LMNA
SCHEMBL6850691 0.99 CA12 (0.60) CA12CA1CA2CA9LMNA
SCHEMBL1234766 0.99 CA12 (0.60) CA12CA1CA2CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1812 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3097171-B1 FLUORESCENT BRIGHTENER PREMIX PROCTER & GAMBLE (US) 2020-06-24 EP claimed
EP-2427540-B1 SHADING COMPOSITION UNILEVER PLC (GB) 2015-11-25 EP claimed
EP-2521764-B1 DETERGENT FORMULATION CONTAINING SPRAY DRIED GRANULE UNILEVER PLC (GB) 2014-11-26 EP claimed
EP-2300589-B1 SHADING COMPOSITION UNILEVER PLC (GB) 2013-10-23 EP claimed
EP-2331670-B1 CATIONIC ISOTHIAZOLIUM DYES UNILEVER PLC NO 41424 (GB) 2013-04-17 EP claimed
EP-2382299-B1 INCORPORATION OF DYE INTO GRANULAR LAUNDRY COMPOSITION UNILEVER PLC (GB) 2013-03-13 EP claimed
US-20090218544-A1 BLEACHING COMPOSITION COMPRISING AN ALKOXYLATED BENZOIC ACID THE PROCTER & GAMBLE COMPANY (US) 2009-09-03 US claimed
EP-1462564-B1 Bleaching composition comprising trimethoxy benzoic acid or a salt thereof PROCTER & GAMBLE (US) 2009-01-21 EP claimed
US-20080261855-A1 Bleaching composition comprising an alkoxylated benzoic acid BRIATORE ANDREA 2008-10-23 US claimed
EP-1614742-B1 Bleaching composition comprising a cyclic hindered amine PROCTER & GAMBLE (US) 2007-12-05 EP claimed
US-20060183657-A1 Bleaching composition comprising a cyclic hindered amine THE PROCTER & GAMBLE COMPANY (US) 2006-08-17 US claimed
WO-2006010089-A1 BLEACHING COMPOSITION COMPRISING A CYCLIC HINDERED AMINE THE PROCTER & GAMBLE COMPANY (US) 2006-01-26 WO claimed
EP-1614742-A1 Bleaching composition comprising a cyclic hindered amine THE PROCTER & GAMBLE COMPANY (US) 2006-01-11 EP claimed
US-20040192571-A1 Bleaching composition comprising an alkoxylated benzoic acid THE PROCTER & GAMBLE COMPANY 2004-09-30 US claimed
EP-1462564-A1 Bleaching composition comprising trimethoxy benzoic acid or a salt thereof THE PROCTER & GAMBLE COMPANY (US) 2004-09-29 EP claimed
EP-0578872-B1 Detergent compositions PROCTER & GAMBLE (US) 1998-10-14 EP claimed
US-5773399-A STORAGE STABILITY FOR DETERGENTS USING SURFACTANTS, SILICATE, SULFATE SALTS WITH PERCARBONATE BLEACHING AGENTS THE PROCTER & GAMBLE COMAPNY (US) 1998-06-30 US claimed
US-5466802-A Surfactant, builder, polymer dye transfer inhibitors and optical brighteners THE PROCTER & GAMBLE COMPANY (US) 1995-11-14 US claimed
US-4216111-A Stable dispersions of fluorescent whitening agents of the bis-triazinylaminostilbene group in free acid form and method of preparing same HICKSON & WELCH LIMITED (GB) 1980-08-05 US claimed
US-4146496-A ALKALI METAL N-BROMO ARYL SULFONAMIDE PROMOTER COLGATE-PALMOLIVE COMPANY (US) 1979-03-27 US claimed