Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.62 |
| ▸ | PPARD | Q03181 | 10/20 | 0.62 |
| ▸ | PPARA | Q07869 | 10/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616373 | 0.93 | PPARG (0.65) | PPARGPPARDPPARAFFAR1 | |
| SCHEMBL4614402 | 0.86 | PPARG (0.68) | PPARGPPARDPPARAFFAR1MMP13 | |
| SCHEMBL4616524 | 0.86 | PPARG (0.59) | PPARGPPARDPPARAMMP13 | |
| SCHEMBL4616843 | 0.86 | PPARG (0.56) | PPARGPPARDPPARAFFAR1 | |
| SCHEMBL4615231 | 0.83 | PPARA (0.73) | PPARGPPARDPPARA | |
| SCHEMBL4616393 | 0.83 | PPARG (0.63) | PPARGPPARDPPARA | |
| SCHEMBL4614376 | 0.83 | PPARG (0.75) | PPARGPPARDPPARAMMP13 | |
| SCHEMBL4616174 | 0.82 | PPARG (0.86) | PPARGPPARDPPARA | |
| SCHEMBL4617143 | 0.81 | PPARG (0.53) | PPARGPPARDPPARAFFAR1FFAR4 | |
| SCHEMBL4616850 | 0.79 | PPARG (0.63) | PPARGPPARDPPARAFFAR1SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| EP-1697304-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054176-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | PPARG 1/4885PPARD 3/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.