Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TACR3 | P29371 | 8/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354904 | 1.00 | KDM4E (0.55) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL4981224 | 0.93 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL5692604 | 0.93 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL3052280 | 0.93 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL8203094 | 0.91 | KDM4E (0.55) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| Hydrochloric Acid SCHEMBL4410289 | 0.89 | HPGD (0.48) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL7095755 | 0.89 | KDM4E (0.51) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL13451464 | 0.86 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL7096162 | 0.86 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1TACR3PLA2G2A | |
| SCHEMBL14095448 | 0.85 | KMT2A (0.44) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881002-A1 | HCV NS-3 serine protease inhibitors | Tibotec Pharmaceuticals Ltd. (IE) | 2008-01-23 | — | — | EP | disclosed |