Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 16/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689881 | 1.00 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3MAPTMTNR1A | |
| SCHEMBL2702986 | 0.90 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3MTNR1AMTNR1B | |
| SCHEMBL4617393 | 0.78 | SLC6A4 (0.86) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2689095 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4617052 | 0.74 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7094962 | 0.73 | MAPT (0.56) | SLC6A4MAPTMTNR1AMTNR1B | |
| Ammonia Solution, Strong SCHEMBL27509223 | 0.71 | MAPT (0.55) | SLC6A4MAPTMTNR1AMTNR1B | |
| SCHEMBL4614922 | 0.70 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4614928 | 0.70 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4616895 | 0.69 | SLC6A4 (0.86) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771435-A4 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RES INST (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1771435-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | Human Biomolecular Research Institute (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006025920-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2006-03-09 | — | — | WO | disclosed |