Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780044 | 0.79 | EP300 (0.44) | KMT2ACA2MAPK1 | |
| SCHEMBL27859740 | 0.77 | EP300 (0.47) | KMT2A | |
| SCHEMBL27859739 | 0.77 | EP300 (0.47) | KMT2A | |
| SCHEMBL27842346 | 0.77 | EP300 (0.47) | KMT2A | |
| SCHEMBL27859867 | 0.77 | EP300 (0.47) | KMT2A | |
| SCHEMBL27842326 | 0.77 | EP300 (0.47) | KMT2A | |
| SCHEMBL27842402 | 0.77 | EP300 (0.47) | KMT2A | |
| SCHEMBL27842353 | 0.77 | EP300 (0.47) | KMT2A | |
| SCHEMBL27859751 | 0.77 | EP300 (0.47) | KMT2A | |
| SCHEMBL27859752 | 0.77 | EP300 (0.47) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940809-A1 | TETRAZOL DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | Bayer HealthCare AG (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045370-A1 | TETRAZOL DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2007-04-26 | — | — | WO | disclosed |