⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tametraline SCHEMBL30592536 | 1.00 | — | — | |
| Tametraline SCHEMBL1237910 | 1.00 | — | — | |
| Tametraline SCHEMBL1237908 | 1.00 | — | — | |
| Tametraline SCHEMBL7330262 | 1.00 | — | — | |
| Tametraline SCHEMBL11694846 | 1.00 | — | — | |
| Tametraline SCHEMBL4619208 | 1.00 | — | — | |
| Tametraline SCHEMBL30083943 | 0.98 | — | — | |
| Tametraline SCHEMBL7326081 | 0.98 | — | — | |
| Tametraline SCHEMBL11359704 | 0.98 | — | — | |
| Tametraline SCHEMBL3147904 | 0.98 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| EP-1885683-A2 | A HIGHLY STEREOSELECTIVE SYNTHESIS OF SERTRALINE | Hetero Drugs Limited (IN) | 2008-02-13 | — | — | EP | disclosed |
| US-20070260090-A1 | Highly Steroselective Synthesis of Sertraline | HETERO DRUGS LIMITED (IN) | 2007-11-08 | — | — | US | disclosed |
| WO-2006129324-A2 | A HIGHLY STEREOSELECTIVE SYNTHESIS OF SERTRALINE | HETERO DRUGS LIMITED (IN) | 2006-12-07 | — | — | WO | disclosed |
| US-4045488-A | ANTIDEPRESSANTS OR PSYCHOMOTOR STIMULANTS | PFIZER INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4029731-A | TREATING DEPRESSION | PFIZER INC. (US) | 1977-06-14 | — | — | US | disclosed |