Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619748 | 0.85 | AR (0.43) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4621251 | 0.84 | AR (0.47) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4157221 | 0.83 | AR (0.48) | ARPGRS1PR1 | |
| SCHEMBL4146602 | 0.81 | AR (0.46) | ARPGRS1PR1 | |
| SCHEMBL4140157 | 0.80 | AR (0.47) | ARPGR | |
| SCHEMBL4140569 | 0.79 | AR (0.45) | ARPGRRXRARXRBRXRG | |
| SCHEMBL4149682 | 0.78 | AR (0.44) | ARPGRRXRARXRBRXRG | |
| SCHEMBL4153666 | 0.78 | AR (0.45) | ARPGRRXRARXRBRXRG | |
| SCHEMBL4145488 | 0.77 | AR (0.43) | ARPGRRXRARXRBRXRG | |
| SCHEMBL4138496 | 0.77 | AR (0.42) | ARPGRRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888512-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-20 | — | — | EP | claimed |
| WO-2006133216-A2 | 4-SUBSTITUTED ARYLAMINE DERIVATIVES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-12-14 | — | — | WO | claimed |
| EP-1888512-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006133216-A2 | 4-SUBSTITUTED ARYLAMINE DERIVATIVES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-12-14 | — | — | WO | disclosed |