Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 8/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.45 |
| ▸ | CA12 | O43570 | 6/20 | 0.45 |
| ▸ | CA4 | P22748 | 4/20 | 0.45 |
| ▸ | CA5A | P35218 | 4/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.41 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313683 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL13928976 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL9616862 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL6230386 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL3972810 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL4619592 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL8089407 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL314060 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL314061 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA | |
| SCHEMBL1686174 | 1.00 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888125-A2 | POLY(PEPTIDE) AS A CHELATOR: METHODS OF MANUFACTURE AND USES | Board of Regents of the University of Texas System (US) | 2008-02-20 | — | — | EP | disclosed |
| US-20060246005-A1 | Poly(peptide) as a chelator: methods of manufacture and uses | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2006-11-02 | — | — | US | disclosed |
| WO-2006107794-A2 | POLY(PEPTIDE) AS A CHELATOR: METHODS OF MANUFACTURE AND USES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-10-12 | — | — | WO | disclosed |
| US-5756712-A | REPLACING THE ETHER OXYGEN LINKAGE OF OLIGOSACCHARIDES WITH A PEPTIDE LINK, WHERE THE NITROGEN ATOM IS LINKED TO THE ANOMERIC CARBON ATOM OF THE SUGAR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0816375-A1 | GLYCOCONJUGATES OF OPIATED SUBSTANCES | ROLABO SL (ES) | 1998-01-07 | — | — | EP | disclosed |
| US-4554349-A | Aralkyl and aralkenyl glycosides as inhibitors of antigen-specific T-cell proliferation | MERCK & CO., INC. (US) | 1985-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246005-A1 | Poly(peptide) as a chelator: methods of manufacture and uses | VIP, NGLY1, DNPEP | CYP2D6 4869/4885THRB 1340/4885HSD17B10 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.