SCHEMBL4619740

SCHEMBL4619740

Oc1ccccc1CC(Br)CCBr

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.45
CYP2D6 P10635 2/20 0.41
TSHR P16473 2/20 0.41
HIF1A Q16665 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39
AKR1B1 P15121 1/20 0.39
CA12 O43570 4/20 0.38
CA2 P00918 4/20 0.38
IDO1 P14902 2/20 0.38
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
CYP3A4 P08684 1/20 0.37
CA9 Q16790 3/20 0.37
MPO P05164 1/20 0.37
KEAP1 Q14145 1/20 0.37
HTR1A P08908 1/20 0.37
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9751198 0.86 HSPA5 (0.39) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL2875695 0.86 TDP1 (0.32)
SCHEMBL4618539 0.84 HSPA5 (0.48) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL2060682 0.81 HSPA5 (0.54) HSPA5CYP2D6TSHRHIF1ATAAR1
Formaldehyde SCHEMBL2787786 0.79 HSPA5 (0.43) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL7618016 0.79 TSHR (0.41) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL6680543 0.74 CTNNB1 (0.45) CYP2D6CA2SLC6A4
SCHEMBL2876022 0.74 TDP1 (0.30)
SCHEMBL8939979 0.74 HSPA5 (0.50) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL4232509 0.72 HSPA5 (0.48) HSPA5CYP2D6TSHRHIF1ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180327671-A1 FLAME RETARDANT LIQUID SOLUTION, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL-IP AMERICA INC. 2018-11-15 US disclosed
EP-1893680-A1 FLAME RETARDANT COMPOSITION EXHIBITING SUPERIOR THERMAL STABILITY AND FLAME RETARDING PROPERTIES AND USE THEREOF ALBEMARLE CORPORATION (US) 2008-03-05 EP disclosed
US-20070018143-A1 Flame retardant composition exhibiting superior thermal stability and flame retarding properties and use thereof ALBEMARLE CORPORATION 2007-01-25 US disclosed
WO-2006132900-A1 FLAME RETARDANT COMPOSITION EXHIBITING SUPERIOR THERMAL STABILITY AND FLAME RETARDING PROPERTIES AND USE THEREOF ALBEMARLE CORPORATION (US) 2006-12-14 WO disclosed
EP-1627013-A2 STABILIZED FLAME RETARDANT ADDITIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2006-02-22 EP disclosed
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
WO-2004104098-A2 STABILIZED FLAME RETARDANT ADDITIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2004-12-02 WO disclosed
US-20040229982-A1 Stabilized flame retardant additives and their use GOOSSENS DANIELLE F (BE) 2004-11-18 US disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed