Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13535468 | 0.93 | TSHR (0.48) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL12408480 | 0.92 | TSHR (0.52) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL5471268 | 0.86 | TSHR (0.54) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL21540243 | 0.86 | KMT2A (0.55) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL3421333 | 0.86 | KMT2A (0.55) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL16732414 | 0.86 | KMT2A (0.55) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL15528126 | 0.84 | TSHR (0.44) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL14453899 | 0.83 | TSHR (0.61) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL2234953 | 0.83 | TSHR (0.61) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL8644381 | 0.82 | TSHR (0.50) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080213833-A1 | Methods for Obtaining Optically Active Glycidyl Ethers and Optically Active Vicinal Diols from Racemic Substrates | OXRANE (UK) LTD. (GB) | 2008-09-04 | — | — | US | disclosed |
| EP-1885849-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES | Oxyrane UK Limited (GB) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006109198-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES | OXYRANE UK LIMITED (GB) | 2006-10-19 | — | — | WO | disclosed |
| EP-0636064-A4 | LENSES WITH HIGH IMPACT RESISTANCE AND HIGH SCRATCH RESISTANCE. | SOANE TECHNOLOGIES INC (US) | 1998-07-01 | — | — | EP | disclosed |
| EP-0395583-B1 | Wettable, flexible, oxygen permeable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units | CIBA GEIGY AG (CH) | 1997-09-03 | — | — | EP | disclosed |
| EP-0330614-B1 | Wettable, flexible, oxygen permeable, swellable contact lens containing polyoxyalkylene backbone units, and use thereof | CIBA GEIGY AG (CH) | 1997-06-04 | — | — | EP | disclosed |
| EP-0330615-B1 | Wettable, flexible, oxygen permeable, contact lens containing polyoxyalkylene backbone units, and use thereof | CIBA GEIGY AG (CH) | 1995-03-15 | — | — | EP | disclosed |
| EP-0636064-A1 | LENSES WITH HIGH IMPACT RESISTANCE AND HIGH SCRATCH RESISTANCE | SOANE TECHNOLOGIES INC. (US) | 1995-02-01 | — | — | EP | disclosed |
| EP-0330618-B1 | Wettable, rigid gas permeable, substantially non-swellable contact lens | CIBA GEIGY AG (CH) | 1994-11-09 | — | — | EP | disclosed |
| US-5278243-A | Polysiloxanes | SOANE TECHNOLOGIES, INC. (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0330615-A2 | Wettable, flexible, oxygen permeable, contact lens containing polyoxyalkylene backbone units, and use thereof | CIBA-GEIGY AG (CH) | 1989-08-30 | — | — | EP | disclosed |
| EP-0330617-A1 | Wettable, flexible, oxygen permeable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units | CIBA-GEIGY AG (CH) | 1989-08-30 | — | — | EP | disclosed |
| US-4857606-A | Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing polyoxyalkylene backbone units, and use thereof | CIGA-GEIGY CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| US-4780488-A | INTRAOCULAR LENSES | CIBA-GEIGY CORPORATION (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0267158-A1 | Substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units | CIBA-GEIGY AG (CH) | 1988-05-11 | — | — | EP | disclosed |
| US-4740533-A | Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof | CIBA-GEIGY CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0263061-A2 | Substantially non-swellable contact lens containing polyoxyalkylene backbone units | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| US-4256900-A | Fluorescent azolyl benzocoumarin dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4233214-A | FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
| US-4036826-A | Cationic azo dyestuffs with a hydroxyalkylated ammonium group | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213833-A1 | Methods for Obtaining Optically Active Glycidyl Ethers and Optically Active Vicinal Diols from Racemic Substrates | GALE, DERA, GNE | TSHR 4775/4885CA1 1973/4885CA2 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.