Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | UGCG | Q16739 | 2/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15721092 | 1.00 | SSTR4 (0.50) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| SCHEMBL20577640 | 1.00 | SSTR4 (0.50) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| SCHEMBL19575247 | 1.00 | SSTR4 (0.50) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| SCHEMBL7036228 | 0.98 | BCHE (0.49) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| SCHEMBL15721070 | 0.96 | BCHE (0.53) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| Bromide SCHEMBL28007848 | 0.95 | BCHE (0.53) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| SCHEMBL15721118 | 0.95 | BCHE (0.55) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| SCHEMBL15721151 | 0.95 | BCHE (0.55) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| SCHEMBL15721150 | 0.93 | SSTR4 (0.49) | SSTR4SSTR5BCHEACHEL3MBTL1 | |
| SCHEMBL19132634 | 0.91 | BCHE (0.53) | SSTR4SSTR5BCHEACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362031-B1 | PHARMACEUTICALLY ACTIVE PIPERIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-03-19 | — | — | EP | disclosed |