Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505361 | 0.92 | HPGD (0.69) | HPGDHTTPARP15PARP10SRD5A2 | |
| SCHEMBL24407671 | 0.87 | HPGD (0.63) | HPGDHTTPARP15PARP10SRD5A2 | |
| SCHEMBL7800107 | 0.85 | HPGD (0.51) | HPGDHTTPARP15PARP10SRD5A2 | |
| SCHEMBL7658168 | 0.84 | HPGD (0.50) | HPGDHTTPARP15PARP10SRD5A2 | |
| SCHEMBL15908264 | 0.84 | HSD17B10 (0.50) | HPGDHTTPARP15PARP10SRD5A2 | |
| SCHEMBL31124426 | 0.82 | HPGD (0.61) | HPGDHTTPARP15PARP10SRD5A2 | |
| SCHEMBL7804231 | 0.80 | HPGD (0.56) | HPGDHTTPARP15PARP10SRD5A2 | |
| SCHEMBL505520 | 0.78 | LPAR1 (0.68) | HPGDHTTPARP15PARP10SRD5A2 | |
| SCHEMBL6567615 | 0.77 | POLB (0.50) | HPGDHTTHSD17B10KMT2A | |
| SCHEMBL5581520 | 0.77 | PARP10 (0.78) | HPGDPARP15PARP10SRD5A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905169-B1 | Precursors of polybenzoxazoles and polybenzothiazoles | INFINEON TECHNOLOGIES AG (DE) | 2008-04-02 | — | — | EP | disclosed |
| US-6153350-A | Polybenzoxazole and polybenzothiazole precursors | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-11-28 | — | — | US | disclosed |
| EP-0905169-A2 | Precursors of polybenzoxazoles and polybenzothiazoles | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |