Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 5/20 | 0.43 |
| ▸ | NMT2 | O60551 | 4/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317624 | 0.97 | FOLH1 (0.51) | FOLH1GLO1PTGS1GSTK1EGFR | |
| SCHEMBL30361223 | 0.96 | FOLH1 (0.50) | FOLH1GLO1PTGS1GSTK1EGFR | |
| SCHEMBL10795372 | 0.95 | FOLH1 (0.51) | FOLH1GLO1PTGS1GSTK1EGFR | |
| SCHEMBL30064268 | 0.93 | FOLH1 (0.48) | FOLH1GLO1PTGS1GSTK1EGFR | |
| SCHEMBL31734738 | 0.92 | FOLH1 (0.47) | FOLH1GLO1PTGS1GSTK1EGFR | |
| SCHEMBL29568716 | 0.92 | GSR (0.46) | FOLH1GLO1PTGS1GSTK1NMT1 | |
| SCHEMBL29569320 | 0.92 | GSR (0.46) | FOLH1GLO1PTGS1GSTK1NMT1 | |
| SCHEMBL29569055 | 0.92 | GSR (0.46) | FOLH1GLO1PTGS1GSTK1NMT1 | |
| SCHEMBL29569009 | 0.92 | GSR (0.46) | FOLH1GLO1PTGS1GSTK1NMT1 | |
| SCHEMBL29568828 | 0.91 | GSR (0.45) | FOLH1GLO1PTGS1GSTK1NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583765-A4 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | GRENPHARMA LLC (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1583765-A2 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | Grenpharma LLC (US) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004045552-A2 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | GRENPHARMA LLC (US) | 2004-06-03 | — | — | WO | disclosed |