Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4493552 | 0.98 | HRH3 (0.54) | HRH3KMT2APOLBMEN1L3MBTL1 | |
| SCHEMBL4622216 | 0.85 | HRH3 (0.61) | HRH3EPHX2HRH2 | |
| Oxalic Acid SCHEMBL4491372 | 0.84 | HRH3 (0.57) | HRH3KMT2APOLBMEN1EPHX2 | |
| SCHEMBL4620057 | 0.82 | EPHX2 (0.67) | HRH3KMT2AMEN1EPHX2MAPT | |
| SCHEMBL4489261 | 0.82 | HRH3 (0.66) | HRH3KMT2AMEN1EPHX2HRH2 | |
| SCHEMBL4500729 | 0.81 | HRH3 (0.65) | HRH3KMT2AMEN1EPHX2MAPT | |
| Oxalic Acid SCHEMBL4497957 | 0.81 | HRH3 (0.61) | HRH3KMT2APOLBMEN1MAPT | |
| SCHEMBL4621969 | 0.80 | EPHX2 (0.61) | HRH3KMT2AMEN1EPHX2MAPT | |
| SCHEMBL4485900 | 0.80 | HRH3 (0.63) | HRH3KMT2AMEN1EPHX2MAPT | |
| SCHEMBL4487976 | 0.80 | HRH3 (0.63) | HRH3KMT2AMEN1EPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |