Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525613 | 1.00 | DNMT1 (0.56) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL4620688 | 0.96 | DNMT1 (0.55) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL4622574 | 0.90 | DNMT1 (0.57) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL17525785 | 0.90 | DNMT1 (0.57) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL16408816 | 0.90 | DNMT1 (0.57) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL19244073 | 0.86 | DNMT1 (0.73) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL2443777 | 0.86 | DNMT1 (0.73) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL3087159 | 0.85 | DNMT1 (0.56) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL3086724 | 0.83 | DNMT1 (0.59) | DNMT1PKMKMT2ACYP2C19DNMT3B | |
| SCHEMBL3079234 | 0.83 | DNMT1 (0.59) | DNMT1PKMKMT2ACYP2C19DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905763-B1 | N-ACYLIC AMINOACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | NEBOLSIN VLADIMIR EVGENIEVICH (RU) | 2019-05-08 | — | — | EP | disclosed |
| EP-1905763-A1 | N-ACYLIC AMINOACID DERIVATIVES. METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | Nebolsin, Vladimir Evgenievich (RU) | 2008-04-02 | — | — | EP | disclosed |