Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.56 |
| ▸ | PPARA | Q07869 | 6/20 | 0.56 |
| ▸ | MPC2 | O95563 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877848 | 0.91 | PPARG (0.65) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL3370792 | 0.85 | PPARG (0.62) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| Hydrochloric Acid SCHEMBL501421 | 0.85 | PPARG (0.61) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL7836834 | 0.77 | FFAR1 (0.56) | PPARGFFAR1PPARA | |
| SCHEMBL8312136 | 0.75 | FFAR1 (0.87) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL8316232 | 0.74 | FFAR1 (0.84) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL15790336 | 0.73 | PPARG (0.80) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| Rivoglitazone SCHEMBL5319250 | 0.72 | PPARG (1.00) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| Rivoglitazone SCHEMBL2906120 | 0.72 | PPARG (1.00) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL1130792 | 0.72 | PPARG (0.54) | PPARGFFAR1PPARAMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902713-A1 | PHARMACEUTICAL COMPOSITION CONTAINING THIAZOLIDINEDIONE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-03-26 | — | — | EP | claimed |