Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 14/20 | 0.47 |
| ▸ | FYN | P06241 | 5/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462543 | 0.84 | TTK (0.53) | TTKFYN | |
| SCHEMBL462421 | 0.83 | TTK (0.50) | TTKFYNERN1 | |
| SCHEMBL463538 | 0.81 | TTK (0.62) | TTK | |
| SCHEMBL462251 | 0.79 | TTK (0.74) | TTK | |
| SCHEMBL455843 | 0.73 | ERN1 (0.46) | TTKERN1 | |
| SCHEMBL9942373 | 0.73 | TTK (0.50) | TTK | |
| SCHEMBL10279179 | 0.73 | TTK (0.60) | TTK | |
| SCHEMBL9942235 | 0.72 | TTK (0.56) | TTK | |
| SCHEMBL9942245 | 0.72 | TTK (0.56) | TTK | |
| SCHEMBL17103797 | 0.72 | TTK (0.64) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |