Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylate SCHEMBL2036461 | 0.81 | TSHR (0.48) | TSHRALDH1A1HSD17B10 | |
| Butylate SCHEMBL9725729 | 0.81 | TSHR (0.57) | TSHRALDH1A1KMT2AMEN1NPSR1 | |
| Butylate SCHEMBL8021675 | 0.79 | TSHR (0.50) | TSHRALDH1A1TDP1HSD17B10 | |
| Butylate SCHEMBL11689530 | 0.79 | TSHR (0.54) | TSHRALDH1A1HSD17B10 | |
| Butylate SCHEMBL20377728 | 0.79 | TSHR (0.54) | TSHRALDH1A1HSD17B10 | |
| Butylate SCHEMBL10487947 | 0.79 | TSHR (0.54) | TSHRALDH1A1HSD17B10 | |
| Butylate SCHEMBL7778213 | 0.79 | TSHR (0.54) | TSHRALDH1A1HSD17B10 | |
| Butylate SCHEMBL3915229 | 0.79 | TSHR (0.54) | TSHRALDH1A1HSD17B10 | |
| Butylate SCHEMBL1986203 | 0.79 | TSHR (0.54) | TSHRALDH1A1HSD17B10 | |
| Butylate SCHEMBL787504 | 0.79 | TSHR (0.54) | TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118755-A | Hydroxy-terminated polyorganosiloxane, silane bonded to ketoximato groups, curing agent, organo zirconium compound elastomers | TOSHIBA SILICONE CO., LTD. (JP) | 1992-06-02 | — | — | US | claimed |
| CN-105843002-B | Electrophtography photosensor cylindric support and its manufacturing method, Electrophtography photosensor, handle box and imaging device | 富士施乐株式会社 | 2019-11-29 | — | — | CN | disclosed |
| CN-108227418-A | Electric conductivity support, Electrophtography photosensor and handle box | 富士施乐株式会社 | 2018-06-29 | — | — | CN | disclosed |
| CN-108205247-A | Ingot and its preparation method, cylindrical metal component and its preparation method, conductive base, photoreceptor, handle box, image forming apparatus | 富士施乐株式会社 | 2018-06-26 | — | — | CN | disclosed |
| EP-2597494-B1 | METHOD FOR MANUFACTURING NEAR INFRARED REFLECTIVE FILM AND NEAR INFRARED REFLECTIVE BODY PROVIDED WITH SAME | KONICA MINOLTA HOLDINGS INC (JP) | 2018-06-06 | — | — | EP | disclosed |
| CN-107490939-A | Electrophtography photosensor, handle box and image forming apparatus | 富士施乐株式会社 | 2017-12-19 | — | — | CN | disclosed |
| CN-107346096-A | Image forming apparatus | 富士施乐株式会社 | 2017-11-14 | — | — | CN | disclosed |
| CN-106033173-A | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士施乐株式会社 | 2016-10-19 | — | — | CN | disclosed |
| CN-105843002-A | Cylindrical support for electrophotographic photoreceptor and method for manufacturing same, electrophotographic photoreceptor, process cartridge, and image forming apparatus | 富士施乐株式会社 | 2016-08-10 | — | — | CN | disclosed |
| CN-102707590-B | Electrophtography photosensor, image forming apparatus and handle box | FUJI XEROX CORP. (JP) | 2015-09-30 | — | — | CN | disclosed |
| US-7405865-B2 | Liquid for electrophoretic display, display medium and display device using the same | MITSUBISHI PENCIL CO., LTD. (JP) | 2008-07-29 | — | — | US | disclosed |
| EP-1634719-B1 | Ink-jet recording sheet | KONICA MINOLTA HOLDINGS INC (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-20070002427-A1 | Liquid for electrophoretic display and display medium and display employing it | MITSUBISHI PENCIL CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1669798-A1 | LIQUID FOR ELECTROPHORETIC DISPLAY AND DISPLAY MEDIUM AND DISPLAY EMPLOYING IT | Mitsubishi Pencil Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20060055762-A1 | Ink-jet recording sheet | KONICA MINOLTA HOLDINGS, INC. (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1634719-A2 | Ink-jet recording sheet | KONICA MINOLTA HOLDINGS, INC. (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-1527899-A1 | Inkjet recording sheet | Konica Minolta Photo Imaging, Inc. (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-20050089652-A1 | Inkjet recording sheet | KONICA MINOLTA PHOTO IMAGING, INC. | 2005-04-28 | — | — | US | disclosed |
| US-6400492-B1 | Electrophoretic display liquid, and electrophoretic display medium, method and device using the liquid | RICOH COMPANY LIMITED (JP) | 2002-06-04 | — | — | US | disclosed |
| US-5118755-A | Hydroxy-terminated polyorganosiloxane, silane bonded to ketoximato groups, curing agent, organo zirconium compound elastomers | TOSHIBA SILICONE CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |