Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2281562 | 0.85 | CYP2B6 (0.43) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11135785 | 0.85 | CYP2B6 (0.43) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL29364609 | 0.85 | CYP2B6 (0.43) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2289180 | 0.85 | CYP2B6 (0.43) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9208 | 0.85 | CYP2B6 (0.43) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| Iodide SCHEMBL11391336 | 0.83 | CYP2B6 (0.42) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| Benzene SCHEMBL5574850 | 0.83 | CYP2B6 (0.42) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| Water SCHEMBL8849440 | 0.83 | CYP2B6 (0.42) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21064745 | 0.83 | CYP2B6 (0.42) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL939557 | 0.83 | CYP2B6 (0.42) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015960-A | Composition comprising photochromic dyes in ionic solvents | ESSILOR INT | 2011-04-13 | — | — | CN | claimed |
| CN-102015960-B | Composition comprising photochromic dyes in ionic solvents | ESSILOR INT | 2014-11-19 | — | — | CN | disclosed |
| EP-1904886-A2 | OPTICAL COMPONENT WITH CELLS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007023383-A2 | OPTICAL COMPONENT WITH CELLS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2007-03-01 | — | — | WO | disclosed |
| US-5604280-A | PHOTOCHROMIC | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1997-02-18 | — | — | US | disclosed |