Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623272 | 1.00 | APP (0.68) | APPATMLMNASMN1; SMN2ESR1 | |
| SCHEMBL8695972 | 0.90 | APP (0.66) | APPLMNASMN1; SMN2CA12CA1 | |
| SCHEMBL8695969 | 0.90 | APP (0.66) | APPLMNASMN1; SMN2CA12CA1 | |
| SCHEMBL6794960 | 0.88 | APP (0.68) | APPATMLMNASMN1; SMN2ESR1 | |
| SCHEMBL19244249 | 0.88 | APP (0.68) | APPATMLMNASMN1; SMN2ESR1 | |
| SCHEMBL19088247 | 0.88 | APP (0.68) | APPATMLMNASMN1; SMN2ESR1 | |
| SCHEMBL10007931 | 0.88 | APP (0.72) | APPATMLMNASMN1; SMN2ESR1 | |
| SCHEMBL6151754 | 0.88 | APP (0.72) | APPATMLMNASMN1; SMN2ESR1 | |
| SCHEMBL6794964 | 0.88 | APP (0.68) | APPATMLMNASMN1; SMN2ESR1 | |
| SCHEMBL10482468 | 0.87 | APP (0.76) | APPATMLMNASMN1; SMN2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368287-B1 | PROCESS FOR A HOMOGENEOUSLY CATALYZED C-C COUPLING REACTION | DSM IP ASSETS BV (NL) | 2008-03-26 | — | — | EP | disclosed |
| US-6784295-B2 | CARRIED OUT IN THE PRESENCE OF AN INORGANIC BASE OR ORGANIC NITROGEN BASE AND A PALLADIUM COMPLEX CATALYST CONTAINING SECONDARY MONOPHOSPHINES WITH ALIPHATIC, BRANCHED OR CYCLIC SUBSTITUENTS AS LIGANDS | SOLVIAS AG (CH) | 2004-08-31 | — | — | US | disclosed |
| EP-1132361-B1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | SOLVIAS AG (CH) | 2003-05-14 | — | — | EP | disclosed |
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001016057-A1 | COUPLING REACTIONS USING PALLADIUM CATALYSTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-08 | — | — | WO | disclosed |
| US-6194627-B1 | REACTING HALOAROMATIC COMPOUND WITH OLEFIN IN PRESENCE OF PALLADIUM COMPOUND AS CATALYST | AVENTIS RESEARCH & TECHNOLOGY GMBH & CO. KG (DE) | 2001-02-27 | — | — | US | disclosed |
| US-5756527-A | ANTICARCINOGENIC AGENTS | ONTOGEN CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0812830-A1 | Modulators of multi-drug resistances | ONTOGEN CORPORATION (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5698755-A | Process for preparing aromatic olefins using palladacycle catalysis | HOECHST AG (DE) | 1997-12-16 | — | — | US | disclosed |