Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623313 | 1.00 | HSD17B3 (0.62) | HSD17B3MAOBTLR9CRHBPCRHR2 | |
| SCHEMBL4055668 | 0.88 | CA12 (0.53) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13845314 | 0.88 | CA12 (0.53) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4055672 | 0.88 | CA12 (0.53) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4031315 | 0.86 | HSD17B3 (0.45) | HSD17B3MAOBTLR9CRHBPCRHR2 | |
| SCHEMBL4065768 | 0.83 | CA12 (0.49) | MAPTKMT2AMEN1HDAC3HDAC4 | |
| SCHEMBL4065769 | 0.83 | CA12 (0.49) | MAPTKMT2AMEN1HDAC3HDAC4 | |
| SCHEMBL23254546 | 0.81 | HSD17B3 (0.68) | HSD17B3MAOBTLR9CRHBPCRHR2 | |
| SCHEMBL8091741 | 0.81 | CA12 (0.66) | MAOBTLR9MAPTKMT2AMAOA | |
| SCHEMBL1322439 | 0.81 | KMT2A (0.54) | MAPTKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368287-B1 | PROCESS FOR A HOMOGENEOUSLY CATALYZED C-C COUPLING REACTION | DSM IP ASSETS BV (NL) | 2008-03-26 | — | — | EP | disclosed |