Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | FABP7 | O15540 | 2/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248824 | 0.88 | KMT2A (0.39) | KMT2APTPN1FABP7FABP5CASP3 | |
| SCHEMBL2245573 | 0.88 | KMT2A (0.39) | KMT2APTPN1FABP7FABP5CASP3 | |
| SCHEMBL2251705 | 0.86 | KMT2A (0.42) | KMT2APTPN1FABP7FABP5CASP3 | |
| SCHEMBL2247795 | 0.85 | KMT2A (0.39) | KMT2APTPN1FABP7FABP5SMN1; SMN2 | |
| SCHEMBL2252327 | 0.85 | PTPN1 (0.37) | KMT2APTPN1FABP7FABP5 | |
| SCHEMBL2246665 | 0.84 | KMT2A (0.41) | KMT2APTPN1FABP7FABP5CASP3 | |
| SCHEMBL2248394 | 0.84 | FABP5 (0.41) | KMT2APTPN1FABP7FABP5LMNA | |
| SCHEMBL2251584 | 0.83 | PTPN1 (0.42) | KMT2APTPN1FABP5 | |
| SCHEMBL2248528 | 0.82 | KMT2A (0.42) | KMT2APTPN1FABP7FABP5CASP3 | |
| SCHEMBL2244782 | 0.82 | KMT2A (0.42) | KMT2APTPN1FABP7FABP5CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902014-A2 | GLUTAMATE AGGRECANASE INHIBITORS | Wyeth (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007008994-A2 | GLUTAMATE AGGRECANASE INHIBITORS | WYETH (US) | 2007-01-18 | — | — | WO | disclosed |