Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 17/20 | 0.75 |
| ▸ | ITGAV | P06756 | 2/20 | 0.75 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626562 | 0.91 | ITGB1 (0.72) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL3315324 | 0.87 | ITGB1 (0.77) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL8352229 | 0.86 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL3313356 | 0.86 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL3316398 | 0.86 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL3313373 | 0.86 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7ITGA5 | |
| SCHEMBL4419511 | 0.85 | ITGB1 (0.83) | ITGB1ITGAVITGA4ITGB7ITGB3 | |
| SCHEMBL3318272 | 0.82 | ITGB1 (0.85) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3316690 | 0.82 | ITGB1 (0.85) | ITGB1ITGAVITGA4ITGB7ITGB2 | |
| SCHEMBL1029639 | 0.82 | ITGB1 (0.89) | ITGB1ITGAVITGA4ITGB7ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | claimed |
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | claimed |
| EP-1434557-B1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | HENKEL KGAA (DE) | 2005-11-09 | — | — | EP | claimed |
| EP-1585489-A2 | AGENT FOR DYEING FIBRES CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-19 | — | — | EP | claimed |
| WO-2004058203-A2 | AGENT FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (US) | 2004-07-15 | — | — | WO | claimed |
| EP-1432428-A1 | Agent for colouring fibres containing keratin | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| WO-2003030842-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300133-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1200051-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | claimed |
| WO-2001013866-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-03-01 | — | — | WO | claimed |
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | disclosed |
| EP-1501801-B1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF VLA-4 DEPENDENT DISEASES | UCB PHARMA SA (BE) | 2008-01-23 | — | — | EP | disclosed |
| EP-1870402-A1 | 2,6-quinolinyl and 2,6-naphthyl derivatives, processes for preparing them and their uses as VLA-4 inhibitors | UCB Pharma, S.A. (BE) | 2007-12-26 | — | — | EP | disclosed |
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | disclosed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | disclosed |
| EP-1300133-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | disclosed |
| EP-1200051-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001013866-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-03-01 | — | — | WO | disclosed |