⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455686 | 0.67 | — | — | |
| SCHEMBL17850589 | 0.67 | — | — | |
| SCHEMBL82321 | 0.59 | — | — | |
| SCHEMBL1187 | 0.59 | — | — | |
| Diethyl Sulfide SCHEMBL1327 | 0.59 | — | — | |
| SCHEMBL7414350 | 0.59 | — | — | |
| Diethyl Sulfide SCHEMBL11391850 | 0.59 | — | — | |
| Diethyl Sulfide SCHEMBL5092086 | 0.59 | TSHR (0.33) | — | |
| Diethyl Sulfide SCHEMBL25414913 | 0.56 | — | — | |
| SCHEMBL3469257 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649638-B1 | 5-Pyridin-3-yl-1H-pyrazole-3-carboxylic amide derivatives; cancer, restenosis, psoriasis, endometriosis, atherosclerosis, viral or yeast infection, and corneal neovascularization treatment | PPD DISCOVERY, INC. | 2003-11-18 | — | — | US | claimed |
| EP-0819982-A1 | Radiation-sensitive composition | Olin Microelectronic Chemicals, Inc. (US) | 1998-01-21 | — | — | EP | claimed |
| EP-1446375-B1 | DIHALOGENPROPENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AS PEST CONTROL AGENTS | BAYER CROPSCIENCE SA (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-6949551-B2 | Dihalopropene compounds, processes for their preparation, compositions comprising them and their use as pesticides | BAYER CROPSCIENCE S.A. (FR) | 2005-09-27 | — | — | US | disclosed |
| EP-1446375-A1 | DIHALOGENPROPENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AS PEST CONTROL AGENTS | Bayer CropScience S.A. (FR) | 2004-08-18 | — | — | EP | disclosed |
| US-20040029886-A1 | Dihalopropene compounds, processes for their preparation, compositions comprising them and their use as pesticides | MERIAL, INC. | 2004-02-12 | — | — | US | disclosed |
| US-6649638-B1 | 5-Pyridin-3-yl-1H-pyrazole-3-carboxylic amide derivatives; cancer, restenosis, psoriasis, endometriosis, atherosclerosis, viral or yeast infection, and corneal neovascularization treatment | PPD DISCOVERY, INC. | 2003-11-18 | — | — | US | disclosed |
| WO-2003042147-A1 | DIHALOGENPROPENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AS PEST CONTROL AGENTS | BAYER CROPSCIENCE S.A. (FR) | 2003-05-22 | — | — | WO | disclosed |
| EP-0877730-B1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO TECHNOLOGY LLC (US) | 2002-10-02 | — | — | EP | disclosed |
| US-6117873-A | CAN BE USED FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS WHICH RESPOND TO BLOCKAGE OF EXCITATORY AMINO ACID RECEPTORS | NOVARTIS AG (CH) | 2000-09-12 | — | — | US | disclosed |
| EP-0934326-A1 | SUBSTITUTED AMINOALKANE PHOSPHONIC ACIDS | Novartis AG (CH) | 1999-08-11 | — | — | EP | disclosed |
| US-4565812-A | Fungicidal tin salts of thienyl and furyl hydroxamic acids, compositions, and method of use therefor | CHEVRON RESEARCH COMPANY (US) | 1986-01-21 | — | — | US | disclosed |
| US-4536391-A | REACTING A PLASMIN HEAVY CHAIN WITH UROKINASE IN THE PRESENCE OF A COUPLING AGENT | OTSUKA PHARMACEUTICAL CO. (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0109653-A2 | Process for preparing urokinase complex | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-05-30 | — | — | EP | disclosed |
| US-4269836-A | ANTIINFLAMMATORY AGENTS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; SEDATIVES | E. R. SQUIBB & SONS, INC. (US) | 1981-05-26 | — | — | US | disclosed |
| US-4128645-A | ANTIINFLAMMATORY, CNS DEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4127657-A | ANTIINFLAMMATORY, CNS DEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4070466-A | ANTIINFLAMMATORY, CNS DEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-01-24 | — | — | US | disclosed |
| US-4061632-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4000277-A | 3,11-Dihydro- 6H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[4,3-d]pyrimidin-6-one and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1976-12-28 | — | — | US | disclosed |