Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.79 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | COMT | P21964 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinterenol SCHEMBL11538969 | 0.88 | CYP2C19 (1.00) | CYP2C19HIF1AIDO1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL30339888 | 0.81 | CYP2C19 (0.64) | CYP2C19HIF1AKDM4ERAB9AMAPT | |
| Hydrochloric Acid SCHEMBL28360013 | 0.81 | CYP2C19 (0.64) | CYP2C19HIF1AKDM4ERAB9AMAPT | |
| SCHEMBL28124508 | 0.77 | CYP2C19 (0.66) | CYP2C19HIF1AIDO1KDM4EHTT | |
| SCHEMBL28124509 | 0.77 | CYP2C19 (0.66) | CYP2C19HIF1AIDO1KDM4EHTT | |
| SCHEMBL14456227 | 0.76 | CYP2C19 (0.64) | CYP2C19HIF1AIDO1KDM4EHTT | |
| SCHEMBL13797358 | 0.75 | CYP2C19 (0.62) | CYP2C19HIF1AIDO1KDM4EHTT | |
| SCHEMBL11277500 | 0.73 | CYP2C19 (0.60) | CYP2C19HIF1AIDO1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL29089156 | 0.71 | KDM4E (0.52) | CYP2C19HIF1AIDO1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL28404971 | 0.71 | HIF1A (0.61) | CYP2C19HIF1AIDO1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | claimed |
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | disclosed |
| EP-1896393-A1 | THE TREATMENT OF INFLAMMATORY DISORDERS AND PAIN | Sosei R&D Ltd. (GB) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007003896-A1 | THE TREATMENT OF INFLAMMATORY DISORDERS AND PAIN | SOSEI R & D LTD. (GB) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | HRH3, OPRL1, HRH2 | CYP2C19 2793/4885HIF1A 1202/4885IDO1 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.