Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626461 | 1.00 | PDK2 (0.54) | PDK2PDK1PDK3PDK4HSD11B1 | |
| SCHEMBL4657256 | 0.89 | PDK2 (0.55) | PDK2PDK1PDK3PDK4HSD11B1 | |
| SCHEMBL4625119 | 0.89 | PDK2 (0.55) | PDK2PDK1PDK3PDK4HSD11B1 | |
| SCHEMBL4625122 | 0.89 | PDK2 (0.55) | PDK2PDK1PDK3PDK4HSD11B1 | |
| SCHEMBL4624781 | 0.87 | PDK2 (0.56) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL4626762 | 0.87 | PDK2 (0.56) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL4624785 | 0.87 | PDK2 (0.56) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL4626767 | 0.87 | PDK2 (0.56) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL4626722 | 0.87 | PDK2 (0.54) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL4626718 | 0.87 | PDK2 (0.54) | PDK2PDK1PDK3PDK4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214287-B1 | AMIDES AS INHIBITORS FOR PYRUVATE DEHYDROGENASE | ASTRAZENECA AB (SE) | 2008-07-02 | — | — | EP | disclosed |