SCHEMBL4626548

SCHEMBL4626548

O=P(O)(O)OC(c1ccccc1)C(Cl)CCl

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.44
ACP3 P15309 7/20 0.38
PGK1 P00558 2/20 0.37
PGK2 P07205 2/20 0.37
POLB P06746 1/20 0.36
CYP2D6 P10635 1/20 0.35
PDPK1 O15530 1/20 0.35
MTOR P42345 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1045500 0.81 SRC (0.48) SRCACP3PGK1PGK2POLB
SCHEMBL4954582 0.75 SRC (0.50) SRCACP3PGK1PGK2POLB
SCHEMBL1725537 0.75 SRC (0.50) SRCACP3POLBKDM4E
SCHEMBL9550963 0.74 SRC (0.48) SRCACP3PGK1PGK2POLB
SCHEMBL4399160 0.71 SRC (0.46) SRCCYP2D6
SCHEMBL613995 0.70 SRC (0.52) SRCACP3PGK1PGK2POLB
SCHEMBL4918156 0.70 CYP3A4 (0.49) SRCACP3POLBCYP2D6KDM4E
SCHEMBL5722203 0.69 SRC (0.50) SRCACP3PGK1PGK2POLB
SCHEMBL9550967 0.67 SRC (0.48) SRCACP3PGK1PGK2POLB
SCHEMBL516900 0.67 HCAR2 (0.49) SRCACP3POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1293500-B1 Method for preparation of acrylonitrile solutions of maleimides NIPPON CATALYTIC CHEM IND (JP) 2008-06-11 EP disclosed
US-6733693-B1 LOWERING THE WATER CONTENT IN THE ACRYLONITRILE SOLUTION NIPPON SHOKUBAI CO., LTD. (JP) 2004-05-11 US disclosed
EP-0768300-B1 Acrylonitrile solutions of maleimides NIPPON CATALYTIC CHEM IND (JP) 2003-05-07 EP disclosed
EP-1293500-A2 Method for preparation of acrylonitrile solutions of maleimides Nippon Shokubai Co., Ltd. (JP) 2003-03-19 EP disclosed
EP-0790334-B1 Easily dyeable meta-linkage-containing aromatic polyamide fibres TEIJIN LTD (JP) 2000-09-27 EP disclosed
US-5993687-A MANIFESTING TRANSPARENCY, PRECLUDING COLORATION AND OPACIFICATION DURING THE COURSE OF HANDLING, AND EXCELLING IN STABILITY; CONTAINING ALKYL-SUBSTITUTED PHENOL OR HINDERED PHENOLS AND A PHOSPHITE, PHOSPHATE, PHOSPHINE OR PHOSPHORAMIDE NIPPON SHOKUBAI, LTD. (JP) 1999-11-30 US disclosed
US-5852087-A Easily dyeable meta-linkage-containing aromatic polyamide fibers TEIJIN LIMITED (JP) 1998-12-22 US disclosed
EP-0790334-A1 Easily dyeable meta-linkage-containing aromatic polyamide fibres TEIJIN LIMITED (JP) 1997-08-20 EP disclosed
EP-0768300-A1 Acrylonitrile solutions of maleimides, method for preparation thereof, and acrylonitrile based copolymers obtained by use of the solutions NIPPON SHOKUBAI CO., LTD. (JP) 1997-04-16 EP disclosed
US-3985661-A LUBRICANT-ABSORBING POWDER CARRIER SUMITOMO ELECTRIC INDUSTRIES, LTD. (JA) 1976-10-12 US disclosed