Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628179 | 0.86 | TSHR (0.44) | KDM4EL3MBTL1 | |
| SCHEMBL4627081 | 0.84 | NR1H2 (0.33) | KDM4EL3MBTL1GRM6DPP4DPP8 | |
| SCHEMBL4628288 | 0.82 | IGF1R (0.34) | KDM4EL3MBTL1GRM6DPP4DPP8 | |
| SCHEMBL4626909 | 0.80 | TSHR (0.48) | KDM4EL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL4627999 | 0.80 | GRM6 (0.36) | KDM4EL3MBTL1GRM6CRHBPCRHR2 | |
| SCHEMBL2689910 | 0.77 | GRM6 (0.40) | L3MBTL1GRM6CRHBPCRHR2EGFR | |
| SCHEMBL6272306 | 0.75 | KDM4E (0.37) | KDM4EL3MBTL1DPP4DPP8DPP9 | |
| SCHEMBL27468466 | 0.75 | GRM6 (0.41) | GRM6CRHBPCRHR2EGFR | |
| SCHEMBL6908945 | 0.73 | TSHR (0.42) | DPP4DPP8DPP9 | |
| Ethane SCHEMBL4642769 | 0.73 | KDM4E (0.43) | KDM4EL3MBTL1GRM6CYP2C9SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209172-B1 | SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION | TOHO TITANIUM CO LTD (JP) | 2008-07-02 | — | — | EP | disclosed |
| US-6770586-B2 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| US-20030130109-A1 | Solid catalyst component and catalyst for olefins polymerization | TOHO TITANIUM CO., LTD (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1209172-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION | Toho Titanium Co., Ltd. (JP) | 2002-05-29 | — | — | EP | disclosed |