Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786057 | 1.00 | EPHX1 (0.43) | EPHX1KDM4EATMGAAL3MBTL1 | |
| SCHEMBL1168484 | 1.00 | EPHX1 (0.43) | EPHX1KDM4EATMGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL18554671 | 0.98 | EPHX1 (0.42) | EPHX1KDM4EATMGAAL3MBTL1 | |
| SCHEMBL9950713 | 0.98 | EPHX1 (0.40) | EPHX1KDM4EATMGAAL3MBTL1 | |
| SCHEMBL17743405 | 0.93 | — | — | |
| SCHEMBL31491232 | 0.88 | — | — | |
| SCHEMBL15592922 | 0.84 | KMT2A (0.35) | EPHX1KDM4EATMGAAHTT | |
| SCHEMBL15188477 | 0.80 | SLC6A4 (0.36) | EPHX1ALDH1A1 | |
| SCHEMBL17046219 | 0.80 | EPHX1 (0.50) | EPHX1KDM4EATMGAAL3MBTL1 | |
| SCHEMBL25476883 | 0.79 | EPHX1 (0.40) | EPHX1KDM4EATMGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635018-A1 | 4-(1H-2-METHYLIMIDAZO 4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1995-01-25 | — | — | EP | claimed |
| WO-1991007430-A1 | PEPTIDES CONTAINING CYCLIC TRIPEPTIDES | THE UPJOHN COMPANY (US) | 1991-05-30 | — | — | WO | claimed |
| EP-1972615-A1 | CYCLOALKANECARBOXAMIDE DERIVATIVE AND METHOD FOR PRODUCING SAME | SEIKAGAKU CORPORATION (JP) | 2008-09-24 | — | — | EP | disclosed |
| EP-1917073-A1 | COMPOSITION FOR DEPILATION | Tex-A-Tec AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| WO-2006136441-A1 | COMPOSITION FOR DEPILATION | TEX-A-TEC AG (CH) | 2006-12-28 | — | — | WO | disclosed |
| US-5214129-A | Amidation of a protected amino acid by an di-O-protected dihydroxy-containing amine and coupling with a carboxylic acid; deprotecting; renin inhibitors; hypotensive agents | ABBOTT LABORATORIES (US) | 1993-05-25 | — | — | US | disclosed |
| US-5091575-A | Renin inhibitor | ABBOTT LABORATORIES (US) | 1992-02-25 | — | — | US | disclosed |
| WO-1991007430-A1 | PEPTIDES CONTAINING CYCLIC TRIPEPTIDES | THE UPJOHN COMPANY (US) | 1991-05-30 | — | — | WO | disclosed |
| US-4870183-A | RENIN INHIBITORS, HYPOTENSIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0252727-A1 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-01-13 | — | — | EP | disclosed |
| EP-0184855-A2 | Resin inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-06-18 | — | — | EP | disclosed |