⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13666492 | 1.00 | — | — | |
| SCHEMBL8256440 | 1.00 | — | — | |
| SCHEMBL12955447 | 0.70 | — | — | |
| SCHEMBL13093809 | 0.70 | — | — | |
| SCHEMBL5423188 | 0.70 | — | — | |
| SCHEMBL11294178 | 0.70 | — | — | |
| SCHEMBL11294175 | 0.70 | — | — | |
| SCHEMBL5423192 | 0.70 | — | — | |
| SCHEMBL387196 | 0.69 | — | — | |
| SCHEMBL19034080 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877830-B2 | Stress relief for crosslinked polymers | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2014-11-04 | — | — | US | disclosed |
| US-8404758-B2 | Stress relaxation in crosslinked polymers | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-03-26 | — | — | US | disclosed |
| US-20120202917-A1 | Stress Relief for Crosslinked Polymers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-09 | — | — | US | disclosed |
| US-20120016052-A1 | Stress Relaxation in Crosslinked Polymers | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2012-01-19 | — | — | US | disclosed |
| WO-2008136642-A1 | NAPHTHOQUINONE-BASED PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES | MAZENCE INC. (KR) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008066300-A1 | NAPHTHOQUINONE-BASED PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES | MAZENCE INC. (KR) | 2008-06-05 | — | — | WO | disclosed |
| EP-1567515-A4 | NOVEL LAPACHONE COMPOUNDS AND METHODS OF USE THEREOF | ARQULE INC (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1567515-A2 | NOVEL LAPACHONE COMPOUNDS AND METHODS OF USE THEREOF | ARQULE, INC. (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004045557-A2 | NOVEL LAPACHONE COMPOUNDS AND METHODS OF USE THEREOF | ARQULE, INC. (US) | 2004-06-03 | — | — | WO | disclosed |
| US-5679834-A | ACID CATALYZED ESTERIFICATION USING ACRYLIC OR METHACRYLIC ACID AS SOLVENT | FUJI PHOTO FILM CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |