SCHEMBL4629337

SCHEMBL4629337

NCC(=O)NC(C(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 1/20 0.41
▸ FNTB P49356 1/20 0.41
▸ GLRA1 P23415 1/20 0.40
▸ SLC6A9 P48067 1/20 0.40
▸ OR51E2 Q9H255 1/20 0.40
▸ CTSC P53634 3/20 0.39
▸ GABRR1 P24046 3/20 0.33
▸ MMP2 P08253 1/20 0.33
▸ TGFBR1 P36897 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ CNR2 P34972 1/20 0.31
▸ TERT O14746 1/20 0.31
▸ GSR P00390 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2259056 0.87 FNTA (0.42) FNTAFNTBGLRA1SLC6A9OR51E2
SCHEMBL31074340 0.85 FNTA (0.34) FNTAFNTBCTSCTHRBRECQL
SCHEMBL7864321 0.79 CTSC (0.37) GLRA1SLC6A9OR51E2CTSCMMP2
SCHEMBL11468148 0.79 CTSC (0.45) CTSCMMP2CNR2
SCHEMBL10703635 0.78 FNTA (0.41) FNTAFNTBOR51E2TGFBR1ALDH1A1
SCHEMBL11445805 0.78 FNTA (0.41) FNTAFNTBALDH1A1THRBRECQL
SCHEMBL24130617 0.77 GNPAT (0.39) GLRA1SLC6A9OR51E2CTSCTGFBR1
SCHEMBL3145911 0.77 SMN1; SMN2 (0.50) CTSCGABRR1ALDH1A1
SCHEMBL783990 0.77 SMN1; SMN2 (0.50) CTSCGABRR1ALDH1A1
SCHEMBL564562 0.77 SMN1; SMN2 (0.50) CTSCGABRR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1618117-B1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF TRUSTEES EWHA WOMANS UNIVERSIT (KR) 2008-04-23 — — EP claimed
EP-1618117-A4 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF TRUSTEES EWHA WOMANS UNIVERSIT (KR) 2007-04-11 — — EP claimed
EP-1618117-A1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF Board of Trustees, Ewha Womans University (KR) 2006-01-25 — — EP claimed
US-6951953-B2 Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof EWHA WOMANS UNIVERSITY (KR) 2005-10-04 — — US claimed
WO-2004096820-A1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF BOARD OF TRUSTEES, EWHA WOMANS UNIVERSITY (KR) 2004-11-11 — — WO claimed
US-20040219127-A1 Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof EWHA WOMANS UNIVERSITY (KR) 2004-11-04 — — US claimed
EP-1618117-B1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF TRUSTEES EWHA WOMANS UNIVERSIT (KR) 2008-04-23 — — EP disclosed
EP-1618117-A4 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF TRUSTEES EWHA WOMANS UNIVERSIT (KR) 2007-04-11 — — EP disclosed
EP-1618117-A1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF Board of Trustees, Ewha Womans University (KR) 2006-01-25 — — EP disclosed
US-6951953-B2 Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof EWHA WOMANS UNIVERSITY (KR) 2005-10-04 — — US disclosed
WO-2004096820-A1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF BOARD OF TRUSTEES, EWHA WOMANS UNIVERSITY (KR) 2004-11-11 — — WO disclosed
US-20040219127-A1 Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof EWHA WOMANS UNIVERSITY (KR) 2004-11-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040219127-A1 Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof PHOSPHO1, FOLR1, PCNA FNTA 3576/4885FNTB 2554/4885GLRA1 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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