Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 4/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293323 | 0.94 | S1PR2 (0.40) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL294020 | 0.92 | S1PR2 (0.42) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL293664 | 0.88 | GBA1 (0.31) | GBA1 | |
| SCHEMBL292787 | 0.85 | S1PR2 (0.39) | GLB1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL293407 | 0.83 | GLB1 (0.39) | GLB1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL7251366 | 0.81 | S1PR2 (0.49) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL7247868 | 0.81 | S1PR2 (0.49) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL7252063 | 0.81 | S1PR2 (0.49) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL7254044 | 0.81 | S1PR2 (0.49) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL293106 | 0.81 | S1PR2 (0.42) | S1PR2S1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |