Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.48 |
| ▸ | LAP3 | P28838 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401796 | 0.98 | GRIK1 (0.50) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL27922903 | 0.98 | GRIK1 (0.50) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL5968376 | 0.98 | GRIK1 (0.50) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL27918872 | 0.98 | GRIK1 (0.50) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL1562732 | 0.87 | TSHR (0.49) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL1562175 | 0.85 | TSHR (0.51) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL1562265 | 0.85 | TSHR (0.51) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL9586888 | 0.85 | TSHR (0.51) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| Butane SCHEMBL5052484 | 0.85 | TSHR (0.47) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL9586357 | 0.85 | TSHR (0.51) | GRIK1GRIK2SLC1A2SLC1A1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008058722-A1 | REAGENT AND USE THEREOF FOR THE PRODUCTION OF BISPHOSPHONATES | SANDOZ A/S (DK) | 2008-05-22 | — | — | WO | disclosed |
| EP-1923394-A1 | Reagent and use thereof for the production of bisphosphonates | Sandoz A/S (DK) | 2008-05-21 | — | — | EP | disclosed |