⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438483 | 0.76 | — | — | |
| SCHEMBL15796666 | 0.75 | — | — | |
| SCHEMBL23800839 | 0.74 | — | — | |
| SCHEMBL15796465 | 0.70 | — | — | |
| SCHEMBL2190039 | 0.69 | — | — | |
| SCHEMBL7565163 | 0.68 | — | — | |
| SCHEMBL448494 | 0.67 | — | — | |
| SCHEMBL633053 | 0.67 | — | — | |
| SCHEMBL1398334 | 0.63 | — | — | |
| SCHEMBL9860543 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931767-B1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | NOVARTIS AG (CH) | 2017-11-08 | — | — | EP | disclosed |
| US-9541676-B2 | Amphiphilic siloxane-containing vinylic monomers and uses thereof | NOVARTIS AG (CH) | 2017-01-10 | — | — | US | disclosed |
| US-9268064-B2 | Amphiphilic siloxane-containing (meth)acrylamides and uses thereof | NOVARTIS AG (CH) | 2016-02-23 | — | — | US | disclosed |
| US-20150309213-A1 | AMPHIPHILIC SILOXANE-CONTAINING VINYLIC MONOMERS AND USES THEREOF | ALCON INC. (CH) | 2015-10-29 | — | — | US | disclosed |
| US-20150301228-A1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | ALCON INC. (CH) | 2015-10-22 | — | — | US | disclosed |
| EP-2931767-A1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | Novartis AG (CH) | 2015-10-21 | — | — | EP | disclosed |
| US-9103965-B2 | Amphiphilic siloxane-containing vinylic monomers and uses thereof | NOVARTIS AG (CH) | 2015-08-11 | — | — | US | disclosed |
| US-9097840-B2 | Amphiphilic siloxane-containing (meth)acrylamides and uses thereof | NOVARTIS AG (CH) | 2015-08-04 | — | — | US | disclosed |
| EP-2307190-B1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2015-03-18 | — | — | EP | disclosed |
| US-8883928-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2014-11-11 | — | — | US | disclosed |
| US-20140171539-A1 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF | NOVARTIS AG (CH) | 2014-06-19 | — | — | US | disclosed |
| US-20140171542-A1 | AMPHIPHILIC SILOXANE-CONTAINING VINYLIC MONOMERS AND USES THEREOF | NOVARTIS AG (CH) | 2014-06-19 | — | — | US | disclosed |
| US-20120065331-A1 | SILICONE-CONTAINING POLYMERIC MATERIALS WITH HYDROLYZABLE GROUPS | ALCON INC. (CH) | 2012-03-15 | — | — | US | disclosed |
| US-8079703-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2011-12-20 | — | — | US | disclosed |
| EP-2307190-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | Novartis AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010011493-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| US-20100014047-A1 | Silicone-Containing Polymeric Materials with Hydrolyzable Groups | ALCON INC. (CH) | 2010-01-21 | — | — | US | disclosed |
| US-4038293-A | Silicone-compatible tris(trimethylsilyloxy)silylalkylamino-substituted quinoncid dyestuffs | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-3981859-A | Silicone-compatible azo dyestuffs | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-09-21 | — | — | US | disclosed |
| US-3963744-A | Silicone-compatible phthalocyanine dyestuffs | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-06-15 | — | — | US | disclosed |