Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 3/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294268 | 0.94 | GLB1 (0.42) | GLB1GBA1SPHK1GUSB | |
| SCHEMBL1615494 | 0.89 | GLB1 (0.55) | GLB1CYP1A2GBA1SPHK1GUSB | |
| SCHEMBL292272 | 0.86 | GLB1 (0.33) | GLB1GBA1 | |
| SCHEMBL7127893 | 0.86 | — | — | |
| SCHEMBL14621071 | 0.86 | — | — | |
| SCHEMBL1031928 | 0.86 | — | — | |
| SCHEMBL294624 | 0.83 | GLB1 (0.44) | GLB1CYP1A2GBA1SPHK1GUSB | |
| SCHEMBL294012 | 0.82 | GLB1 (0.50) | GLB1CYP1A2GBA1SPHK1GUSB | |
| SCHEMBL294460 | 0.79 | GBA1 (0.41) | GLB1GBA1SPHK1GUSB | |
| SCHEMBL293950 | 0.79 | GBA1 (0.41) | GLB1GBA1SPHK1GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |