Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.47 |
| ▸ | HTR2B | P41595 | 13/20 | 0.47 |
| ▸ | HTR2A | P28223 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629662 | 0.82 | HTR2C (0.45) | HTR2CHTR2BHTR2A | |
| SCHEMBL2702455 | 0.81 | EPHX2 (0.56) | HTR2CHTR2BHTR2A | |
| SCHEMBL4629646 | 0.74 | HTR2A (0.39) | HTR2CHTR2BHTR2A | |
| SCHEMBL615931 | 0.70 | EPHX2 (0.59) | HTR2C | |
| Hydrochloric Acid SCHEMBL23124285 | 0.69 | EPHX2 (0.58) | HTR2C | |
| Hydrochloric Acid SCHEMBL10317373 | 0.69 | EPHX2 (0.58) | HTR2C | |
| Hydrochloric Acid SCHEMBL20339507 | 0.69 | EPHX2 (0.58) | HTR2C | |
| SCHEMBL4661839 | 0.68 | HTR2C (0.36) | HTR2CHTR2BHTR2A | |
| SCHEMBL8662643 | 0.67 | HTR2C (0.33) | HTR2CHTR2BHTR2A | |
| SCHEMBL8663947 | 0.66 | HTR2C (0.40) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |