Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290280 | 0.96 | MEN1 (0.48) | MEN1KMT2ANPSR1LMNAHTT | |
| SCHEMBL2298146 | 0.96 | MEN1 (0.48) | MEN1KMT2ANPSR1LMNAHTT | |
| SCHEMBL25184925 | 0.90 | HPGD (0.48) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL2293121 | 0.90 | HPGD (0.48) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL2292500 | 0.90 | HPGD (0.48) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL2292909 | 0.88 | GRM2 (0.54) | MEN1KMT2ANPSR1LMNATP53 | |
| SCHEMBL2294186 | 0.88 | GRM2 (0.54) | MEN1KMT2ANPSR1LMNATP53 | |
| SCHEMBL2290463 | 0.85 | KMT2A (0.50) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2293140 | 0.85 | KMT2A (0.50) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2298062 | 0.85 | DRD4 (0.46) | MEN1KMT2AALDH1A1POLBDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910320-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-04-16 | — | — | EP | claimed |
| WO-2007011065-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-25 | — | — | WO | claimed |