Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17358752 | 0.90 | HSD17B10 (0.41) | HSD17B10NPC1UCHL1EPHX2NR1H2 | |
| SCHEMBL8235326 | 0.90 | HSD17B10 (0.41) | HSD17B10NPC1UCHL1EPHX2NR1H2 | |
| SCHEMBL30289230 | 0.90 | HSD17B10 (0.41) | HSD17B10NPC1UCHL1EPHX2NR1H2 | |
| SCHEMBL4864314 | 0.87 | NR1H2 (0.45) | HSD17B10NPC1UCHL1EPHX2NR1H2 | |
| SCHEMBL10269872 | 0.87 | NR1H2 (0.45) | HSD17B10NPC1UCHL1EPHX2NR1H2 | |
| SCHEMBL18084470 | 0.87 | NR1H2 (0.45) | HSD17B10NPC1UCHL1EPHX2NR1H2 | |
| SCHEMBL16168073 | 0.86 | NR1H2 (0.39) | HSD17B10NPC1UCHL1EPHX2NR1H2 | |
| SCHEMBL3817711 | 0.85 | HSD17B10 (0.40) | HSD17B10NPC1UCHL1EPHX2NR1H2 | |
| SCHEMBL15606327 | 0.84 | HSD17B10 (0.47) | HSD17B10NPC1UCHL1NR1H2LMNA | |
| SCHEMBL10215478 | 0.84 | NPC1 (0.41) | HSD17B10NPC1UCHL1EPHX2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984323-A1 | VIRAL POLYMERASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007087717-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-09 | — | — | WO | disclosed |