SCHEMBL4632004

SCHEMBL4632004

CN1Cc2nc(C(=O)N[C@H]3C[C@@H](C(=O)N(C)C)CC[C@@H]3NC(=O)c3cc4ccc(Cl)cc4nn3)sc2C1

nearest known ligand 0.89

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.89
F2 P00734 1/20 0.62
PLAT P00750 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632001 1.00 F10 (0.89) F10F2PLAT
Hydrochloric Acid SCHEMBL1504018 0.99 F10 (0.88) F10F2PLAT
Hydrochloric Acid SCHEMBL1504020 0.99 F10 (0.88) F10F2PLAT
SCHEMBL1253903 0.94 F10 (1.00) F10F2PLAT
SCHEMBL1253902 0.94 F10 (1.00) F10F2PLAT
Hydrochloric Acid SCHEMBL1504329 0.94 F10 (0.99) F10F2PLAT
Hydrochloric Acid SCHEMBL1504327 0.94 F10 (0.99) F10F2PLAT
SCHEMBL1252869 0.89 F10 (0.90) F10F2PLAT
Hydrochloric Acid SCHEMBL3310755 0.88 F10 (0.88) F10F2PLAT
SCHEMBL12101160 0.88 F10 (1.00) F10F2PLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1925611-B1 OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME DAIICHI SANKYO CO LTD (JP) 2016-04-13 EP disclosed
EP-1925611-A1 OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME Daiichi Sankyo Company, Limited (JP) 2008-05-28 EP disclosed