Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21134801 | 0.87 | ACE (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21134716 | 0.87 | ACE (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21135091 | 0.87 | ACE (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21153021 | 0.87 | ACE (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21134859 | 0.87 | ACE (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21134850 | 0.87 | ACE (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL21134977 | 0.87 | ACE (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL1158100 | 0.86 | — | — | |
| SCHEMBL499352 | 0.86 | — | — | |
| SCHEMBL340834 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1584615-B1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | OREAL (FR) | 2008-05-28 | — | — | EP | claimed |