Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150690 | 0.85 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631830 | 0.83 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL4631475 | 0.83 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL6151709 | 0.83 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL4631361 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151279 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151304 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL27468571 | 0.81 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL6150936 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| Toluene SCHEMBL27455218 | 0.81 | EDNRA (0.77) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1498418-B1 | Sulfonamides for treatment of endothelin-mediated disorders | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-05-21 | — | — | EP | disclosed |