Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 4/20 | 0.33 |
| ▸ | MMP13 | P45452 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737146 | 0.88 | PPARG (0.43) | PPARGCNR1CNR2METTPH1 | |
| SCHEMBL27716295 | 0.79 | PPARG (0.44) | PPARGCNR1CNR2METADRB3 | |
| SCHEMBL3206619 | 0.76 | PPARG (0.42) | PPARGCNR1CNR2MMP2MMP3 | |
| SCHEMBL28771266 | 0.76 | PPARG (0.43) | PPARGCNR1CNR2MMP2MMP3 | |
| SCHEMBL27737202 | 0.75 | PPARG (0.43) | PPARGMETADRB3 | |
| SCHEMBL27716255 | 0.75 | PPARG (0.44) | PPARGCNR1CNR2MET | |
| SCHEMBL27716297 | 0.74 | PPARG (0.43) | PPARGMET | |
| SCHEMBL27716270 | 0.74 | PPARG (0.43) | PPARGCNR1CNR2METTPH1 | |
| SCHEMBL27737216 | 0.74 | PPARG (0.40) | PPARGRAB9A | |
| SCHEMBL3213102 | 0.73 | CNR1 (0.38) | PPARGCNR1CNR2METAGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |