Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633302 | 0.97 | S1PR2 (0.48) | MEN1KMT2AKDM4ESMN1; SMN2S1PR2 | |
| SCHEMBL4633251 | 0.97 | S1PR2 (0.48) | MEN1KMT2AKDM4ESMN1; SMN2S1PR2 | |
| SCHEMBL4632564 | 0.97 | S1PR2 (0.48) | MEN1KMT2AKDM4ESMN1; SMN2S1PR2 | |
| SCHEMBL4291915 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4ESMN1; SMN2S1PR2 | |
| SCHEMBL4633568 | 0.86 | S1PR2 (0.48) | MEN1KMT2ASMN1; SMN2S1PR2S1PR1 | |
| SCHEMBL4294295 | 0.85 | S1PR2 (0.49) | MEN1KMT2AKDM4ESMN1; SMN2S1PR2 | |
| SCHEMBL4286993 | 0.85 | S1PR2 (0.49) | MEN1KMT2AKDM4ESMN1; SMN2S1PR2 | |
| SCHEMBL4291911 | 0.85 | S1PR2 (0.49) | MEN1KMT2AKDM4ESMN1; SMN2S1PR2 | |
| SCHEMBL4633518 | 0.83 | S1PR5 (0.47) | S1PR1S1PR3 | |
| SCHEMBL4633616 | 0.83 | S1PR5 (0.47) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650186-B1 | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-06-04 | — | — | EP | claimed |