Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 11/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.51 |
| ▸ | TUBB | P07437 | 3/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196905 | 0.88 | IDO1 (0.52) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3183415 | 0.84 | IDO1 (0.41) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3542875 | 0.82 | IDO1 (0.49) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3198637 | 0.78 | IDO1 (0.51) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3185709 | 0.77 | IDO1 (0.43) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5988151 | 0.76 | IDO1 (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3183462 | 0.76 | SLC6A4 (0.47) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3190980 | 0.76 | HTR2A (0.51) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3193834 | 0.76 | IDO1 (0.57) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5989667 | 0.76 | IDO1 (0.57) | IDO1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701940-B1 | 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRI | LUNDBECK & CO AS H (DK) | 2008-05-28 | — | — | EP | disclosed |