Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14887353 | 1.00 | MAPT (0.41) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| SCHEMBL14887474 | 1.00 | MAPT (0.41) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| SCHEMBL14989441 | 1.00 | MAPT (0.41) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| SCHEMBL14887223 | 1.00 | MAPT (0.41) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| SCHEMBL14989440 | 1.00 | MAPT (0.41) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| SCHEMBL15574890 | 1.00 | MAPT (0.41) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| SCHEMBL11878704 | 1.00 | MAPT (0.41) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL17005231 | 0.98 | MAPT (0.40) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL17005232 | 0.98 | MAPT (0.40) | MAPTLMNACYP2C9CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL15574844 | 0.98 | MAPT (0.40) | MAPTLMNACYP2C9CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287472-B | Antiviral 4'-substituted pre-nucleotide phosphoramidates | HOFFMANN LA ROCHE | 2011-10-12 | — | — | CN | disclosed |
| CN-101287472-A | Antiviral 4'-substituted pre-nucleotide phosphoramidates | ROCHE PALO ALTO LLC (CH) | 2008-10-15 | — | — | CN | disclosed |
| EP-1928475-A2 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-SUBSTITUTED PRONUCLEOTIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007020193-A2 | ANTIVIRAL PHOSPHORAMIDATES OF 4 ' -SUBSTITUTED PRONUCLEOTIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-22 | — | — | WO | disclosed |