Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633208 | 0.97 | TLR7 (0.53) | TLR7 | |
| SCHEMBL4634184 | 0.91 | TLR7 (0.57) | TLR7 | |
| SCHEMBL4666608 | 0.91 | TLR7 (0.61) | TLR7 | |
| SCHEMBL2840336 | 0.89 | TLR7 (0.66) | TLR7 | |
| SCHEMBL2862789 | 0.88 | TLR7 (0.60) | TLR7 | |
| SCHEMBL30164530 | 0.87 | TLR7 (0.71) | TLR7 | |
| SCHEMBL13798671 | 0.87 | TLR7 (0.71) | TLR7 | |
| SCHEMBL5964498 | 0.86 | TLR7 (0.64) | TLR7 | |
| SCHEMBL1244619 | 0.86 | TLR7 (0.62) | TLR7 | |
| SCHEMBL4132122 | 0.85 | TLR7 (0.60) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928876-A1 | PURINE DERIVATIVES HAVING IMMUNO-MODULATING PROPERTIES | AstraZeneca AB (SE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007031726-A1 | PURINE DERIVATIVES HAVING IMMUNO-MODULATING PROPERTIES | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | WO | disclosed |