Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634397 | 1.00 | EGFR (0.42) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4634400 | 0.99 | EGFR (0.43) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4133773 | 0.99 | EGFR (0.41) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4133774 | 0.99 | EGFR (0.41) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4128340 | 0.98 | EGFR (0.42) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4128343 | 0.98 | EGFR (0.42) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4133775 | 0.98 | EGFR (0.42) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4131728 | 0.97 | EGFR (0.40) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4131731 | 0.97 | EGFR (0.40) | EGFRPTPN1ERBB2LMNACYP1A2 | |
| SCHEMBL4131733 | 0.96 | EGFR (0.41) | EGFRPTPN1ERBB2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | disclosed |