Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634520 | 1.00 | NR1H4 (0.51) | NR1H4PTGDR2PDE4BPDE4DIKBKB | |
| SCHEMBL4120866 | 0.82 | PTGS1 (0.48) | NR1H4PDE4BPDE4D | |
| SCHEMBL4120873 | 0.82 | PTGS1 (0.48) | NR1H4PDE4BPDE4D | |
| Acetic Acid SCHEMBL4634751 | 0.79 | CYP26A1 (0.37) | NR1H4NPC1CASP3RAB9ASENP7 | |
| Acetic Acid SCHEMBL4634752 | 0.79 | CYP26A1 (0.37) | NR1H4NPC1CASP3RAB9ASENP7 | |
| Acetic Acid SCHEMBL4635060 | 0.78 | DHODH (0.39) | NPC1CASP3RAB9ASENP7 | |
| Acetic Acid SCHEMBL4635062 | 0.78 | DHODH (0.39) | NPC1CASP3RAB9ASENP7 | |
| Acetic Acid SCHEMBL4129774 | 0.78 | CSNK2A2 (0.35) | NPC1CASP3RAB9ASENP7 | |
| SCHEMBL4134807 | 0.76 | NR1H4 (0.50) | NR1H4PDE4BPDE4D | |
| SCHEMBL4134811 | 0.76 | NR1H4 (0.50) | NR1H4PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |