⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402298 | 0.82 | — | — | |
| SCHEMBL2598017 | 0.72 | POLB (0.31) | — | |
| SCHEMBL7159812 | 0.64 | — | — | |
| SCHEMBL6643089 | 0.62 | — | — | |
| SCHEMBL11115953 | 0.62 | — | — | |
| SCHEMBL1275406 | 0.61 | — | — | |
| SCHEMBL2745811 | 0.60 | — | — | |
| SCHEMBL8080821 | 0.58 | — | — | |
| SCHEMBL6129688 | 0.57 | — | — | |
| SCHEMBL1311693 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928845-A2 | AMINODIAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Array Biopharma, Inc. (US) | 2008-06-11 | — | — | EP | claimed |
| WO-2007040840-A2 | AMINODIAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | ARRAY BIOPHARMA INC. (US) | 2007-04-12 | — | — | WO | claimed |