Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634770 | 1.00 | HDAC1 (0.31) | HDAC1HDAC2HPGDTDP1 | |
| SCHEMBL4143537 | 0.86 | HDAC1 (0.31) | HDAC1HDAC2 | |
| SCHEMBL4143541 | 0.86 | HDAC1 (0.31) | HDAC1HDAC2 | |
| SCHEMBL4120885 | 0.83 | HPGD (0.34) | HPGDTDP1 | |
| SCHEMBL4120886 | 0.83 | HPGD (0.34) | HPGDTDP1 | |
| SCHEMBL4140153 | 0.77 | HDAC1 (0.32) | HDAC1HDAC2HPGDTDP1 | |
| SCHEMBL4140156 | 0.77 | HDAC1 (0.32) | HDAC1HDAC2HPGDTDP1 | |
| SCHEMBL4132819 | 0.76 | HDAC1 (0.36) | HDAC1HDAC2 | |
| SCHEMBL4133702 | 0.76 | MEN1 (0.37) | HDAC1 | |
| SCHEMBL4133696 | 0.76 | MEN1 (0.37) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | disclosed |